Cannabis: Uses and Risks | Dr. Andrew Huberman | The Tim Ferriss Show
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Andrew Huberman, PhD (@hubermanlab), is a neuroscientist and tenured professor in the Department of Neurobiology at Stanford University’s School of Medicine. He has made numerous important contributions to the fields of brain development, brain function, and neural plasticity. Work from the Huberman Laboratory at Stanford Medicine has been consistently published in top journals including Nature, Science, and Cell.
Andrew is the host of the podcast Huberman Lab, which is often ranked as one of the top five podcasts in the world by both Apple and Spotify. The show aims to help viewers and listeners improve their health with science and science-based tools. New episodes air every Monday on YouTube and all podcast platforms.
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Tim Ferriss is one of Fast Company’s “Most Innovative Business People” and an early-stage tech investor/advisor in Uber, Facebook, Twitter, Shopify, Duolingo, Alibaba, and 50+ other companies. He is also the author of five #1 New York Times and Wall Street Journal bestsellers: The 4-Hour Workweek, The 4-Hour Body, The 4-Hour Chef, Tools of Titans and Tribe of Mentors. The Observer and other media have named him “the Oprah of audio” due to the influence of his podcast, The Tim Ferriss Show, which has exceeded 900 million downloads and been selected for “Best of Apple Podcasts” three years running.
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Comments (33)
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If your a lazy unmotivated piece of shit.. then smoking weed or not your going still be a lazy piece of shit
I can say I function on edibles to a degree..its def better than Xanax. However it takes between 75-100mg daily as an effective dose. Anything more is a bit of a hangover but less is not effective. I didnt do drugs as a kid and my stuff was more trauma and Military and the meds they give me are too strong.
Huberman speaking on cannabis as a non user is intriguing
Whenever I have 0 to no tolerance and I smoke weed, I talk with demons and endlessly create beats in my head.
volcano vape ftw
Bob Hope no hope.
Amateur Health Researcher with over 20 years experience. Science based facts. The cannabis of today, sold legally in shops is designed for potency and does indeed have psychoactive properties. It forces a change in brain chemistry, no small thing. This needs to be taken seriously and driving or operating machinery while high is extremely dangerous. It is highly addictive, period. The difference is that withdrawal symptoms are very mild and mostly psychological. I had a close friend who defended cannabis usage to the point where his multi-million dollar real estate holdings were all gone and he was living in a van in the mountains outside San Diego. Heavy pot smokers typically turn very negative and steal from others. They also make life very difficult for those around them. Tens of thousands of rural properties have been seized simply because users will attempt to grow in a restricted area. Smoking pot causes atrophy of the thymus gland, the master gland of the immune system, (not well known by medical professionals.)
alcohol is way safer than cannabis for the reason that you know more obviously how much is ok or not. With Cannabis its wayy easier to not see a dangerous point of usage, its much more unpredictable. Also, cannabis changes your worldview much more strongly than alcohol does. With alcohol, people degrade their physical body. But with cannabis, people become 'stoners' who begin to not take life as seriously anymore. Cannabis an also make you suddenly 'snap' and cause you to enter into a different and bad psychological state of mind. Very scary.
Has someone looked into schizophrenia and cannabis (AND the mutation COMT or not)?? IMHO that's something to look at!
What about regulated vs not regulated? I’ve heard there’s significantly less chances of mental health issues… due to what’s sprayed on it. (Eagle something?)
High potency is less harmful because less needs to be smoked or vaped.
How can Tim say mdma is not a psychedelic. It’s as if he is implying MDMA less dangerous than the cannabis plant.
Hmm?
2.5mg is like 2 hits on a joint. Why bother
Fuc cannabis it definitely kept me in low vibration
Everything said here is correct but Weeds a weird one. If you treat it like a medicine You will benefit from its response But it’s so easy to abuse & that’s when it’s gonna fuck you up. There’s a difference between smoking everyday & smoking all day every Day.
there is not "almost pure cannabis available"…. the strongest flower (bud) is about 40% thc….. concentrated wax or distillate is not a cannabis flower
It works for me but it's not for everybody apparently which meaning your mileage may vary person to person on how they can handle cannabinoids in the CB1 and 2 receptors there is also a new one out there called thca which is hemp derived and it is perfectly legal it does in fact hit just like the illegal version of Delta 9 that we all know and love
Blaming homelessness on pot is utter REEFER MADNESS 😂
If I use cannabis only occasionally will it still effect my dopamine levels negatively?
I started smoking cigarettes since my teenage, spent my whole life fighting Cigarettes addiction. Also suffered severe depression and mental disorder. Not until my mom recommended me to psilocybin mushrooms treatment. Psilocybin treatment saved my life honestly. 8 years totally clean. This is something that really need to be use globally to help people with related health challenges.
I lost my brother 18 years ago to “cannabis induced psychosis” which ultimately led to his demise. This is commonly known about in the mental health wards, the outcome for schizophrenia is low because ultimately they end up taking their lives or accidentally overdosing on other things. To drown out the voices. Interestingly- it’s is young men, late teens to early 20s. But what wasn’t mentioned here is that women in late 30s are at higher risk too. I’m extremely careful now I’m in this bracket, and clearly it’s in my genes. It breaks my heart to imagine all the gravestones and people who have gone out this way. He loved to smoke so I’m not against anyone here but I’m not going to tread lightly when I’ve seen what I’ve seen.
Kids should not use it because there not ready for it it should just be for adults in less its for medical
I smoked weed (also cigarettes) about every day, for more than 40 years, and have been weed and tobacco free for almost 10 years and I feel much better now. I still like my beer though. Not a lot, but a few after work.
3:00 "I would feel it but it would not be externally obvious" . . . OK, you believe that Tim but honestly, to me you appear a bit like a stoner
Everything in moderation. Simple as that.
Alot of people smoke tons of weed throughout their whole life and live healthy lives, cannabis increasing risk for psychosis is an unfounded theory and hasn't really been proved.
yeah it can be good medicine if you have mental stuff like me and can get a prescription but only ask for the 7% THC or weaker don’t even touch 25% thc or if you do understand it is not the same substance basically a highly euphoric psychedelic that can 100% be addictive. This also doesn’t mean the weaker 7% can not be addictive it’s just lower potency so less overall effects while still providing you with medicinal effects without giving you a massive tolerance. You can also lower addiction potential by only consuming it in a way where it is not instantly bioavailable such as oils. The key is moderation and seriously this can be hard if you have mental struggles so I give you this advice to start out on the right track. Start off on the strong stuff you will enjoy it for a while and then watch the high go away your motivation drop and time and money go down the drain from your growing addiction. It can be an excellent medicine but it is presented as far too harmless and given to the public at a far higher potency then it really should be. If it was only distributed in weaker potencies at least people would understand how much THC they are consuming if they want to consume that much on occasion which is fine imo as long as your brain has developed. I am a chronic smoker started at 15 trust me on all of this and you will have a much better story to tell about your cannabis use and will find far more gain then negative effects. Really pay attention to this post if you are suffering currently, have addiction in your family or have other mental health issues as you are completely susceptible and potentially at risk of addiction, as I was and it’s terrible consequences down the track (you won’t see until it’s too late trust me friend) if you are considering consuming cannabis. One other key piece of advice I can give is decide if you want to use it recreationally or medicinally (if you suffer from mental illness I would highly recommend choosing medicinally). This means you can practice moderation and maintain the medicinal effects of cannabis that you may need to get to sleep without suffering greatly from all the negatives of daily, chronic high THC doses caused by long term recreational use becoming self medication for mental illness but is actually making it worse in the long run. And when I say moderation I mean it like 2.5mg of THC at night to sleep is a perfect example. Moderation is so key the best thing you can do is only consume 7% or lower THC flower in small doses (0.2g or less) and Oil doses that are 1-5mg THC and that do not exceed 10mg THC per 12 hours. Cannabis used with care medicinally can give so many benefits without any negatives my friends.
Just MY Opinion, IT Nasty.
I love Clean, Clear,🤔ing. Sobermined.
As someone who has severe anxiety from anything resembling an “experienced” dose, 2.5mg has been a game changer and I am so relieved that so many companies have embraced this and make products with a low dose. 2.5mg is more anti-depressant for me than any SSRI or opioid given to me by a doctor and I feel normal, happy and energetic. Companies that make these THC drink shots with 50+mg of THC are doing a disservice to the community.
I microdose edibles. No more than 5 mg at a time. 95% of time it’s between 0-2.5 mg. It 100% helps my mood and gives me a little “inspiration” when I’m feeling burnt out from work or unmotivated. I’ve found it usually shifts my attention to big picture ideas, helping with any type of reflection or planning, and stimulates creativity too. It’s helped me with everything from writing an essay to rethinking a marketing plan to writing a best man speech. Workouts are also improved, I believe due to increased proprioception. I would characterize the overall effects of cannabis at these doses (let’s say 1.5-3 mg) as intoxicating as a cup of coffee.
Anything over 5mg and I risk moving from uplifting, creative, and pleasantly focused to hyper focused anxiety and even possible paranoia or panic attack in very high doses and/or the wrong setting. If you combine a high dose with any type of external pressure, such as a social situation or, this is exasperated.
Dose and setting are important people. The more uncertain your setting is, lower your dose. The higher your dose, ensure an ideal setting away from external stressors. It is a powerful and useful tool I have found a place for in my ambitious and productive lifestyle.
For me with my epilepsy, it keeps me away from thinking negative and being depressed. I can go to work like any other person, I have a full time job and really work hard. Work doesn't make me feel like being lazy for as I have to keep active for time to move. BTW I don't have a prescription for weed, but have take a whole lotta of anticonvulsants that make you feel like a zombie and trigger you to depression and anger as side affect
I started smoking cannabis in my early teens back in the 70s and by today's standards it was extremely low THC and I quit by the time I turned 20. Fast-forward 35-40 years when I started to develop problems with my knees and other joints due to being an adrenaline junkie throughout my late teens through my 30s, military parachuting martial arts etc I started taking no or very low THC CBD and it worked unbearably. A few years ago I started to develop what I now know to be peripheral neuropathy. In a nutshell they put me on gabapentin which took the edge off but really just masked the symptoms. Then I ran into a close friend who was undergoing chemotherapy and he developed it from the chemo drugs and when I asked if he was on gaba he said no that his doctor suggested THC which surprised the hell out of me, so I gave it a try and the difference was like night and day. I take a very low dose during the day around 1.5 mg a few times a day and a higher therapeutic dose thru dry herb vape or vape cartridge at night between 10-20 mg and it also helps me with sleep. I've tried higher dosage but it's actually uncomfortable and doesn't seem to add any benefit. With that I've been able to cut my gaba dose from 3x to 2x a day.